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Bills vs. Jets odds: Opening lines for Week 10 matchup

The Buffalo Bills just laid waste to the Minnesota Vikings in front of a national audience for Monday Night Football, improving to 7-1 on the season. Their reward for having won a hard-fought game against the NFL’s best defense is…

Published: Tuesday, 10 November 2026 at 6:40 AM
Bills vs. Jets odds: Opening lines for Week 10 matchup
Key Things to Know
  • The Buffalo Bills opened as 7.5-point road favorites against the New York Jets in Week 10.
  • The over/under total for the AFC East divisional matchup was set at 50.5 points.
  • Buffalo improved to 7-1 following a Monday Night Football win, while the Jets hold a 2-7 record.
The Story in 60 Seconds

The Buffalo Bills opened as 7.5-point road favorites over the New York Jets for their upcoming Week 10 divisional matchup, according to FanDuel Sportsbook. The over/under line for the contest was set at 50.5 points. Buffalo heads into the game with a 7-1 record after defeating the Minnesota Vikings on Monday Night Football, while the Jets sit at 2-7.

Buffalo enters the contest as the NFL's only undefeated road team this season at 4-0. The Bills have won five consecutive games against the Jets dating back to November 2023 and hold a 12-4 record in the series since quarterback Josh Allen became the starter in 2018.

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