Fantasy Football Week 4: Running game matchups to target

PFF's Nic Bodiford analyzes running game matchups to target for fantasy football managers in Week 4. The breakdown highlights games featuring high-powered offenses and defensive mismatches to help managers maximize their scoring potential. Key featured matchups include the Cincinnati Bengals taking on the Jacksonville Jaguars, alongside the Denver Broncos facing the San Francisco 49ers.

According to the analysis, the Jaguars' run defense faces its most difficult challenge of the season against Cincinnati. Additionally, both the Broncos and 49ers rushing attacks are expected to operate efficiently in their head-to-head clash.