CeeDee Lamb and Kyren Williams came up big in Week 4, while D'Andre Swift and Trevor Lawrence had a disappointing day.

ESPN analysts reviewed the fantasy football winners, losers, and major injuries from Week 4 of the 2026 season. Dallas wide receiver CeeDee Lamb led all performers with a career-high 41.3 fantasy points, recording 17 catches and the game-winning touchdown against Houston. Running backs Kyren Williams and Javonte Williams also posted standout weeks, each exceeding 31 points.
Conversely, D'Andre Swift and quarterback Trevor Lawrence struggled to produce, with Swift losing backfield touches after a third-quarter fumble. Notable injuries occurred across the league, with Saquon Barkley exiting due to a hamstring issue, Lamar Jackson suffering an ankle injury, and Ja'Marr Chase entering the concussion protocol.
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