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Five Key Things to Know About Bills at Rams in Week 5

On Monday night at SoFi Stadium, Joe Brady’s team looks to rebound after a loss to the Patriots vs. a Rams’ team coming off a thrilling win at Philadelphia.

Published: Monday, 12 October 2026 at 1:05 PM
Five Key Things to Know About Bills at Rams in Week 5
Key Things to Know
  • The Buffalo Bills visit the Los Angeles Rams on Monday night looking to rebound from their first loss.
  • Buffalo has committed seven turnovers over its last two games after committing none across the opening two weeks.
  • Rams running back Kyren Williams entered Week 5 ranked among the league leaders with 467 yards from scrimmage.
The Story in 60 Seconds

The Buffalo Bills travel to face the Los Angeles Rams on Monday night at SoFi Stadium following a 29-26 loss to the New England Patriots. Buffalo enters the Week 5 contest aiming to avoid a second consecutive defeat after opening the season with three straight victories. Sean McVay's Rams enter the matchup after rallying to defeat the Philadelphia Eagles 24-20.

Ball security has become an issue for the Bills, who committed seven turnovers over their last two games after recording none in the first two weeks. Los Angeles will rely on running back Kyren Williams, who entered Week 5 with 467 total scrimmage yards, while the Rams' pass protection faces Bills pass rusher Greg Rousseau, who entered the week leading the NFL with six sacks.

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