The Chicago Cubs have faced many players who've completely crushed them in their careers, yet there are some that stand out among the rest…
Ryan O'Rourke lists the 25 biggest "Cubs killers" in Major League Baseball history, examining notable opposing players who repeatedly tormented the Chicago Cubs. The rankings highlight active players and historical figures based on statistical dominance, career damage, and painful franchise moments.
The featured group includes Atlanta Braves second baseman Ozzie Albies at 25th, alongside former stars such as Mark McGwire, Todd Worrell, Lou Brock, Nolan Ryan, and Tom Seaver. O'Rourke details specific feats, including McGwire's 1.285 OPS against Chicago and Brock's standout performances following his trade from the Cubs.
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