Cleveland begins its regular season Thursday night with a challenging road test against Philadelphia at Xfinity Mobile Arena. The 76ers already have a win under their belt after beating the reigning-champion Knicks 106-100 on Tuesday, and Thursday doubles as their…
The Cleveland Cavaliers open their regular season against the Philadelphia 76ers on Thursday, October 22, 2026, at Xfinity Mobile Arena. The game will air nationally on ESPN at 7 p.m. ET. Philadelphia enters the matchup at 1-0 after beating the New York Knicks 106-100 on Tuesday, while Cleveland looks to build on sweeping all four regular-season games against the 76ers last year.
Frontcourt health is the primary storyline, as Cavaliers center Jarrett Allen is questionable with right patellar tendinopathy. Philadelphia faces its own depth issues, with Dean Wade listed as questionable due to an ankle injury alongside multiple frontcourt reserves being ruled out behind Joel Embiid.
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