Broncos vs. 49ers prediction, best bets: Brock Purdy maintains hot start

Malik Smith predicts the San Francisco 49ers will maintain their strong early form against the Denver Broncos at Levi's Stadium. The undefeated 49ers enter Week 4 as 2.5-point favorites, backed by an offense that leads the NFL in yards per play and total touchdowns. Quarterback Brock Purdy has surged into the MVP conversation with 10 total touchdowns and just one interception across his first three appearances.

In contrast, Smith notes that the Broncos are struggling early in games, averaging an NFL-worst 3.3 first-half points per contest behind quarterback Bo Nix. Based on San Francisco's consistent early scoring and Denver's slow starts, Smith's primary betting recommendation is taking the 49ers -1.5 on the first-half spread at -105 odds.