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Matthew Stafford makes unwanted NFL history at worst possible time in Rams’ crushing loss

Matthew Stafford threw the 33rd pick-six of his career against the Broncos, passing Brett Favre for the most in NFL history during the Rams’ 30-26 loss.

Published: Monday, 28 September 2026 at 5:54 AM
Matthew Stafford makes unwanted NFL history at worst possible time in Rams’ crushing loss
Key Things to Know
  • The Denver Broncos defeated the Los Angeles Rams with a final score of 30-26.
  • Matthew Stafford threw his 33rd career pick-six, surpassing Brett Favre for the most in NFL history.
  • Talanoa Hufanga returned Stafford's interception 66 yards for a touchdown in the fourth quarter.
The Story in 60 Seconds

Matthew Stafford became the NFL's all-time leader in pick-sixes thrown during the Los Angeles Rams' 30-26 loss to the Denver Broncos. With 4:49 remaining in the fourth quarter, Denver safety Talanoa Hufanga intercepted a pass intended for Kyren Williams and returned it 66 yards for a touchdown. The play gave Stafford 33 career pick-sixes, surpassing the previous record of 32 held by Brett Favre.

The interception flipped a 19-16 Rams lead into a 23-19 deficit. Following a back-and-forth battle down the stretch, Hufanga sealed Denver's 30-26 victory by intercepting Stafford again in the end zone on the game's final play.

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