Two AFC South rivals, one must-win Sunday in Indianapolis. John Harris breaks down Daniel Jones, Jonathan Taylor, the Buckner-Stewart duo and what Houston has to do to leave Lucas Oil Stadium with win number one.
The Houston Texans travel to face AFC South division rival the Indianapolis Colts at Lucas Oil Stadium on September 27, 2026. Both franchises enter the Week 3 matchup winless with 0-2 records to begin the regular season. The Texans have won their last four consecutive games played against the Colts in Indianapolis.
Indianapolis faces significant challenges under head coach Shane Steichen, with their defense currently ranking last in the league across nearly every category. Colts quarterback Daniel Jones returned to start following a fractured fibula sustained the previous season, while wide receiver Alec Pierce reinjured a heel that required offseason surgery.
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