The San Francisco 49ers have won six of their first seven games despite a revolving door of injuries, but that luck took a hit right before the bye week.Star running back Christian McCaffrey left the 49ers’ 29-20 loss to the…

Indianapolis Colts running back Jonathan Taylor has been linked to the San Francisco 49ers in trade discussions ahead of the November 10 deadline. NBC Sports analyst Chris Simms reported on PFT Live that figures around the NFL are speculating whether San Francisco could pursue Taylor. The 49ers currently face depth concerns following a mild hamstring injury suffered by starting running back Christian McCaffrey during Week 7.
According to Pro Football Talk's Mike Florio, Taylor's remaining 2026 base salary fits within San Francisco's current payroll, though salary cap complexities would arise in 2027. The Colts reportedly opened the door to trading Taylor on October 31, and league executives believe the Pro Bowl running back could command a second-round pick plus an additional selection.
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