Home » Sports » NFL » San Francisco 49ers
The 49ers' first loss of 2026 looked a lot like several losses in 2025, with several key players hobbled or out because of injury.

The San Francisco 49ers suffered their first defeat of the season, falling 29-20 to the Atlanta Falcons. Quarterback Brock Purdy threw two interceptions, including a late fourth-quarter pick to Falcons linebacker Kendal Daniels that sealed Atlanta's victory. The loss dropped San Francisco to a 6-1 record heading into their bye week, ending their undefeated start despite an early 14-3 lead.
San Francisco struggled with four total turnovers and significant offensive absences, playing with only four active wide receivers. Running back Christian McCaffrey missed nearly two quarters after suffering a dead thigh, while top receiver Mike Evans was also sidelined. Tight end George Kittle and Purdy acknowledged that injuries dramatically changed the offensive game plan, though McCaffrey stated he expects to return after the bye.
49ers Move to 6-1 Following Week 7 Matchup vs. Falcons; Takeaways from #SFvsATLSan Francisco 49ers
7 quick reactions to 49ers’ turnover-filled loss to FalconsNiner Noise
49ers’ embarrassing loss to Falcons is the wake-up call they sorely neededNiner Noise
What was Kyle Shanahan’s message to 49ers after sloppy loss to Falcons?49ers Webzone
To provide the best experiences, we and our partners use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us and our partners to process personal data such as browsing behavior or unique IDs on this site and show (non-) personalized ads. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Click below to consent to the above or make granular choices. Your choices will be applied to this site only. You can change your settings at any time, including withdrawing your consent, by using the toggles on the Cookie Policy, or by clicking on the manage consent button at the bottom of the screen.

Get the latest sports news and top stories from MySportsTab delivered straight to your inbox.
No spam. Just the latest sports news and updates.