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49ers Activate Former First-Round Pick in Major Boost Before Seahawks Game

The 49ers have officially welcomed back a former first-round pick, adding much-needed firepower to their depleted defensive front ahead of Sunday's game against the Seahawks.

By Erik C. Anderson · Heavy

Published: Saturday, 10 October 2026 at 10:32 PM

Key Things to Know

The 49ers activated defensive end Mykel Williams from the Reserve/PUP list ahead of Sunday's game against Seattle.
Williams is cleared to play after missing nearly a year due to a torn ACL suffered in November 2025.
His return provides depth with defensive lineman Nick Bosa ruled out with knee and calf injuries.

The Story in 60 Seconds

The San Francisco 49ers activated defensive end Mykel Williams from the Reserve/Physically Unable to Perform list on Saturday, October 10. The 2025 No. 11 overall draft pick had been sidelined since suffering a torn ACL in November 2025 and is cleared to make his season debut against the Seattle Seahawks.

Williams' return bolsters an injury-depleted defensive line overseen by defensive coordinator Raheem Morris, which will be without Nick Bosa and James Thompson Jr. The team also re-signed veteran Ogbo Okoronkwo to the practice squad and elevated him alongside tight end Jack Stoll.

Read the full article on Heavy

49ers Activate Former First-Round Pick in Major Boost Before Seahawks Game

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