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Commanders vs. Giants odds: Opening lines for Week 5 matchup

The Washington Commanders are 1-3 after their international loss to the Indianapolis Colts. They were in good shape until Marcus Mariota went down with another MCL injury. He is likely to miss time, and he was replaced in today’s game…

Published: Sunday, 4 October 2026 at 11:00 PM
Commanders vs. Giants odds: Opening lines for Week 5 matchup
Key Things to Know
  • The Washington Commanders opened as 3.5-point home favorites against the New York Giants for Week 5.
  • The over/under point total for the NFC East divisional matchup opened at 44.5.
  • Jayden Daniels is expected to return to practice and start at quarterback for Washington.
The Story in 60 Seconds

The Washington Commanders have opened as 3.5-point home favorites against the New York Giants for their Week 5 matchup. According to FanDuel odds, the over/under total opened at 44.5 points, with Washington listed at -196 on the moneyline and New York at +164. The Commanders enter the divisional contest at 1-3 overall and 0-2 in the NFC East following an international loss to the Indianapolis Colts.

Washington is expected to welcome back starting quarterback Jayden Daniels from a dislocated left elbow, while Marcus Mariota is likely to miss time with an MCL injury. The division-leading 3-1 Giants will start backup quarterback Jameis Winston after Jaxson Dart suffered a season-ending knee injury.

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