Week 5 fantasy football lineups are becoming increasingly difficult to set as injuries, workload splits, and matchup changes create uncertainty across the running back position. Some of the league’s most dependable backs remain obvious starts. However, several players carry enough…

Enzo Flojo of ClutchPoints provides fantasy football recommendations for running backs ahead of Week 5 in 2026. Flojo identifies Jonathan Taylor, Chase Brown, and Christian McCaffrey as top players to start based on workload and matchup advantages. He also names Jaylen Warren and James Cook III as additional start candidates.
Conversely, Flojo recommends benching RJ Harvey, Alvin Kamara, and Will Shipley due to backfield competition and injury concerns. Kamara missed Wednesday's practice with a back issue, while Shipley's value depends heavily on Saquon Barkley's hamstring injury. Tony Pollard and Woody Marks are also listed as players to sit.
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