Cardinals vs. 49ers Week 3: How to watch, injury news, storylines, prediction

The 1-1 Arizona Cardinals travel to face the San Francisco 49ers at Levi's Stadium in a Week 3 divisional matchup on Sunday, September 27. Kickoff is scheduled for 1:05 p.m. MST, with the Cardinals aiming to rebound from a 31-7 loss to the Seattle Seahawks. Cardinals head coach Mike LaFleur previously worked on 49ers head coach Kyle Shanahan's staff for seven consecutive seasons.

San Francisco enters the game with significant injuries, as defensive end Nick Bosa is expected to miss multiple weeks with a calf injury. The 49ers also ruled out Romello Height, Demarcus Robinson, and James Thompson Jr., while veteran wide receiver Mike Evans is listed as questionable with a hip issue.