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49ers’ Deebo Samuel to miss ‘some time’ with hamstring injury, per Kyle Shanahan

Again, the 49ers will be forced to dip into their depth at wide receiver.Deebo Samuel, who was a major contributor to the 49ers’ early-season success, will miss multiple games with a hamstring injury, coach Kyle Shanahan said on Monday.“It’s pretty…

Published: Monday, 12 October 2026 at 1:17 PM
49ers’ Deebo Samuel to miss ‘some time’ with hamstring injury, per Kyle Shanahan
Key Things to Know
  • Deebo Samuel will miss multiple games after suffering a hamstring injury against the Seattle Seahawks.
  • San Francisco 49ers head coach Kyle Shanahan confirmed the injury is significant and will sideline Samuel for some time.
  • Samuel recorded 16 receptions for 206 yards and three receiving touchdowns through the first five games.
The Story in 60 Seconds

San Francisco 49ers wide receiver Deebo Samuel will miss multiple games after sustaining a hamstring injury on Sunday, head coach Kyle Shanahan confirmed. The injury occurred during the second half of the 49ers' 39-32 victory over the Seattle Seahawks. Shanahan described the issue as severe, noting that Samuel will be sidelined for "some time."

Through five games, Samuel posted 16 receptions for 206 yards and three touchdowns, alongside 78 rushing yards. With Samuel sidelined, San Francisco retains four healthy receivers on its 53-man roster, while defensive end Nick Bosa is reportedly nearing a return from a calf injury ahead of the Week 6 matchup against the Washington Commanders.

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