10 Players Who Ended Serena Williams’ Grand Slam Runs

Serena Williams is undoubtedly one of the greatest tennis players of all time.

By Riddhi Acharya · Sportskeeda

Published: Wednesday, 7 October 2026 at 3:45 PM

Key Things to Know

Sportskeeda highlighted 10 notable players who pulled off Grand Slam upsets against 23-time champion Serena Williams.
Roberta Vinci halted Williams' bid for a calendar-year Grand Slam by winning their 2015 US Open semifinal.
Virginie Razzano famously eliminated Williams in the first round of the 2012 French Open.

The Story in 60 Seconds

Riddhi Acharya highlights 10 notable players who caused major upsets against 23-time Grand Slam singles champion Serena Williams at Grand Slam tournaments throughout her career. Despite dominating tennis for more than two decades, the American legend suffered unexpected defeats at various stages across all four major championships.

The featured upsets include Daniela Hantuchova at the 2006 Australian Open, Virginie Razzano at the 2012 French Open, Jill Craybas at Wimbledon in 2005, Roberta Vinci at the 2015 US Open, and Ajla Tomljanovic at Williams' final professional tournament in 2022.

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10 Players Who Ended Serena Williams’ Grand Slam Runs

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